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編 號:hy030006
名 稱:Anti-Nestin,巢蛋白,神經(jīng)上皮干細胞蛋白抗體
來 源:兔
交叉反應:人
克隆類型:多克隆抗體
濃 度:1mg/1ml
性 狀:Lyophilized or Liquid
蛋白分子量:predicted molecular weight: 178kDa
應 用:WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500(石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Anti-Nestin,巢蛋白,神經(jīng)上皮干細胞蛋白抗體保存條件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
備 注:本產(chǎn)品僅供科研實驗使用。(This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications)
Function : Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity).
Subunit : Forms homodimers and homotetramers in vitro. In mixtures with other intermediate filament proteins such as vimentin and alpha-internexin, tis protein preferentially forms heterodimers which can assemble to form intermediate filaments if nestin does not exceed 25%. Interacts with FHOD3 (By similarity).
Tissue Specificity : CNS stem cells.
Similarity : Belongs to the intermediate filament family.