人妻精品久久久久中文字幕青草,999久久久免费看,午夜性爱福利,96无码

行業(yè)產(chǎn)品

  • 行業(yè)產(chǎn)品

廈門慧嘉生物科技有限公司


當(dāng)前位置：廈門慧嘉生物科技有限公司>>細(xì)胞因子>>Prospec >>Noggin Human/重組人Noggin 產(chǎn)品編號：CYT-475

Noggin Human/重組人Noggin 產(chǎn)品編號：CYT-475

返回列表頁
參  考  價面議
具體成交價以合同協(xié)議為準(zhǔn)

產(chǎn)品型號

品       牌

廠商性質(zhì)代理商

所  在  地廈門市

聯(lián)系方式：陳先生查看聯(lián)系方式

更新時間：2015-12-26 23:09:09瀏覽次數(shù)：437次

聯(lián)系我時，請告知來自 環(huán)保在線

經(jīng)營模式：代理商

商鋪產(chǎn)品：9325條

所在地區(qū)：福建廈門市

聯(lián)系人：陳先生

產(chǎn)品簡介

Noggin Human/重組人Noggin 產(chǎn)品編號：CYT-475
產(chǎn)品規(guī)格：5μg/20μg/1mg

詳細(xì)介紹

 

Noggin Human/重組人Noggin

產(chǎn)品編號：CYT-475
產(chǎn)品規(guī)格：5μg/20μg/1mg
 

Synonyms SYM1, SYNS1, NOG.
Introduction The secreted polypeptide noggin, encoded by the NOG gene, binds and inactivates members of the transforming growth factor-beta （TGF-beta） superfamily signaling proteins, such as bone morphogenetic protein-4 （BMP4）. By diffusing through extracellular matrices more efficiently than members of the TGF-beta superfamily, noggin may have a principal role in creating morphogenic gradients. Noggin appears to have pleiotropic effect, both early in development as well as in later stages. It was originally isolated from Xenopus based on its ability to restore normal dorsal-ventral body axis in embryos that had been artificially ventralized by UV treatment. The results of the mouse knockout of noggin suggest that it is involved in numerous developmental processes, such as neural tube fusion and joint formation. Recently, several dominant human NOG mutations in unrelated families with proximal symphalangism （SYM1） and multiple synostoses syndrome （SYNS1） were identified; both SYM1 and SYNS1 have multiple joint fusion as their principal feature, and map to the same region （17q22） as NOG. All NOG mutations altered evolutionarily conserved amino acid residues. The amino acid sequence of human noggin is highly homologous to that of Xenopus, rat and mouse.
Description Noggin Human Recombinant produced in E.Coli is a non-glycosylated, non-disulfide-linked homodimer consisting of two 206 amino acid polypeptide chains, having a total molecular mass of approximay 46.2 kDa （each chain 23.1 kDa）.
Noggin is purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder.
Formulation Lyophilized from a 0.2μm filtered solution in 30% CH3CN, 0.1% TFA.
Solubility It is recommended to be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 10mM HAc to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in appropriate buffered solutions.
Stability Lyophilized Noggin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Noggin should be stored at 4°C between 2-7 days and for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles.
Purity Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence MQHYLHIRPAPSDNLPLVDLIEHPDPIFDPKEKDLNETLLRSLLGGH
YDPGFMATSPPEDRPGGGGGAAGGAEDLAELDQLLRQRPSGAMPS
EIKGLEFSEGLAQGKKQRLSKKLRRKLQMWLWSQTFCPVLYAWNDL
GSRFWPRYVKVGSCFSKRSCSVPEGMVCKPSKSVHLTVLRWRCQR
RGQRCGWIPIQYPIISECKCSC.
Biological Activity The ED50 was determined by its ability to inhibit 5.0 ng/ml of BMP-4 induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The expected ED50 for this effect is 0.05-0.08 μg/ml of Noggin.
Protein content Protein quantitation was carried out by two independent methods
1. UV spectroscopy at 280 nm using the absorbency value of 1.76 as the extinction coefficient for a 0.1% （1mg/ml） solution. This value is calculated by the PC GENE computer analysis program of protein sequences （InliGenetics）.

2. Analysis by RP-HPLC, using a standard solution of Noggin as a Reference Standard.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.


您感興趣的產(chǎn)品PRODUCTS YOU ARE INTERESTED IN

環(huán)保在線 設(shè)計制作，未經(jīng)允許翻錄必究 .? ? ? Copyright(C)?2021 http://szhxt8.com.cn,All rights reserved.

以上信息由企業(yè)自行提供，信息內(nèi)容的真實性、準(zhǔn)確性和合法性由相關(guān)企業(yè)負(fù)責(zé)，環(huán)保在線對此不承擔(dān)任何保證責(zé)任。 溫馨提示：為規(guī)避購買風(fēng)險，建議您在購買產(chǎn)品前務(wù)必確認(rèn)供應(yīng)商資質(zhì)及產(chǎn)品質(zhì)量。

會員登錄

×

請輸入賬號

請輸入密碼

=

請輸驗證碼

收藏該商鋪

請 登錄 后再收藏

提示

您的留言已提交成功！我們將在第一時間回復(fù)您~
99久久免费只有精品国产| 激情中文网| 欧美一级久久久| 囯产16处破女| AV在线区| 欧美日韩国产综合一区二区三区| 精品熟女60老妇av免| www.国产传媒| 双腿张开被9个男人调教| 久久性爱无码| av一级一高清一高清一区| 欧美成人专区| 97人人超碰| 精品麻豆国产| 久久精品国产一区| 一中医馆空刷医保卡超263万| 少妇人妻无码久久久久久| 日韩精品电影一区| 精品国产一区二区三区不卡| 欧美另类亚洲| 久久精品亚洲国产| 中文字幕爆乳巨爆乳系列无码视频| 欧美A高清| 国产精品女同一区二区久久夜| 一级欧美一级日韩| 一区二区三区久久久| 搡老熟女国产AV对白| 精品国产91久久久久久无码蜜臀 | 五月天精品一区二区三区| 亚洲av午夜精品无码专区| 久久久无码人妻精品无码| 亚洲精品社区| 免费亚洲成人电影| 一区二区免费在线观看| 国产一区二区久久精品| 国产无码精品久久| 四季久久免费一区二区三区四区| 亚洲女人被黑人巨大进入| 99精品久久只有精品| 久久av无码αv高潮αv喷吹| 国产精品丝袜视频无码一区69|