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重組人EB病毒誘導(dǎo)因子3/EBI3 Human

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重組人EB病毒誘導(dǎo)因子3/EBI3 Human產(chǎn)品編號(hào)：CYT-367
產(chǎn)品規(guī)格：2μg/10μg/1mg

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重組人EB病毒誘導(dǎo)因子3/EBI3 Human

產(chǎn)品編號(hào)：CYT-367
產(chǎn)品規(guī)格：2μg/10μg/1mg

Catalogue Number	CYT-367
Synonyms	Interleukin-27 subunit beta, IL-27 subunit beta, IL-27B, Epstein-Barr virus-induced gene 3 protein, EBV-induced gene 3 protein, EBI3, IL27B.
Introduction	EBI3 has an induced expression in B lymphocytes in reaction to Epstein-Barr virus infection. EBI3 encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form iIL-27. EBI3 drives rapid clonal expansion of naive cd4（+） t-cells. EBI3 strongly synergizes with IL-12 to activate IFN-gamma production of naive cd4（+） t-cells. EBI3 mediates its biologic effects through the cytokine receptor wsx-1/tccr.
Description	EBI3 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 209 amino acids fragment （21-229） having a molecular weight of 23.3kDa. The EBI3 is purified by proprietary chromatographic techniques.
Source	Escherichia Coli.
Physical Appearence	Sterile Filtered White lyophilized （freeze-dried） powder.
Formulation	EBI3 Human Recombinant was lyophilized from a solution containig 10mM Acetic Acid and 0.5% Mannitol.
Solubility	It is recommended to reconstitute the lyophilized EBI3 in sterile 10mM Acetic acid not less than 100μg/ml, which can then be further diluted to other aqueous solutions.
Stability	Lyophilized EBI3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution EBI3 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.
Purity	Greater than 90% as determined by （a） Analysis by RP-HPLC. （b） Analysis by SDS-PAGE.
Amino Acid Sequence	RKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSF IATYRLGMAARGHSWPCLTPTSTSCTITDVQLFSMAPYVL NVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQ VQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSF ILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATATMSLGK.
Biological Activity	Assay data for Human recombinant EBI3 is based upon qualitative binding to anti-EBI3 antibody.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.