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聯(lián)系我時,請告知來自 環(huán)保在線研盟生物標(biāo)記抗體“Anti-FGFR4/FITC,FITC標(biāo)記的成纖維細(xì)胞生長因子受體4抗體“,規(guī)格100ul,保證品質(zhì),咨詢:
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產(chǎn)品名稱 Anti-FGFR4/FITC,FITC標(biāo)記的成纖維細(xì)胞生長因子受體4抗體
產(chǎn)品編號 BYK-0676R-FITC
英文名稱 Anti-FGFR4/FITC
中文名稱 FITC標(biāo)記的成纖維細(xì)胞生長因子受體4抗體
別 名 CD 334; CD334; CD334 antigen; fc13h 10; fc13h10; Fgfr 4; Fgfr4; Fibroblast growth factor receptor 4; Hydroxyaryl protein kinase; JTK 2; JTK2; MGC20292; Protein tyrosine kinase; TKF; Tyrosine kinase related to fibroblast growth factor receptor; Tyrosylprotein kinase; FGFR4_HUMAN.
研究領(lǐng)域 腫瘤 免疫學(xué) 細(xì)胞膜受體
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog,
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 86kDa
細(xì)胞定位 細(xì)胞膜
性 狀 Lyophilized or Liquid
濃 度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FGFR4
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-FGFR4/FITC,FITC標(biāo)記的成纖維細(xì)胞生長因子受體4抗體產(chǎn)品介紹:The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimay influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.
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