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中文名稱(chēng)：宮頸黏液蛋白相關(guān)蛋白抗體

英文名稱(chēng)：Anti-HIP55 antibody

上海研盟生物科技有限公司Anti-HIP55抗體*，主要應(yīng)用于WB、IHC、IF、ELISA、流式細(xì)胞術(shù)等實(shí)驗(yàn)中。說(shuō)明書(shū)隨貨發(fā)送，您也可以直接我司在線(xiàn)客服索取?？头?.

宮頸黏液蛋白相關(guān)蛋白抗體,Anti-HIP55抗體簡(jiǎn)單介紹：

產(chǎn)品別名：ABP1; Actin-binding protein 1; Cervical mucin associated protein; Cervical mucin-associated protein; Cervical SH3P7; CMAP; Dbnl; DBNL_HUMAN; Drebrin F; drebrin like; Drebrin like protein; Drebrin-F; Drebrin-like protein; HIP 55; HIP-55; HPK1 interacting protein of 55 kDa; HPK1-interacting protein of 55 kDa; SH3 domain containing protein 7; SH3 domain-containing protein 7; SH3P7; Src Homology 3 Domain Containing Protein; src homology 3 domain containing protein HIP.

產(chǎn)品規(guī)格：0.1ml、0.2ml、1ml

產(chǎn)品用途：科研實(shí)驗(yàn)

產(chǎn)品價(jià)格：請(qǐng)報(bào)價(jià)

說(shuō)明書(shū)：請(qǐng)?zhí)砑涌头苯铀魅?/p>

抗體來(lái)源：該指標(biāo)有兩種產(chǎn)品，一種是兔來(lái)源抗體，一種是鼠來(lái)源抗體

克隆類(lèi)型：兔來(lái)源為多克隆抗體，鼠來(lái)源單克隆抗體

交叉反應(yīng)：請(qǐng)索取說(shuō)明書(shū)查看

背景介紹：Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. HIP-55 (HPK1-interacting protein of 55 kDa), also known as ABP1, SH3P7 or DBNL (drebrin-like), is a 430 amino acid cytoplasmic protein that belongs to the ABP1 family. HIP-55 binds to F-actin but is not involved in actin polymerization, capping or bundling. In addition to containing an ADF-H domain, HIP-55 also consists of a SH3 domain, which mediates interaction with SHANK2, SHANK3 and PRAM-1. HIP-55 acts as an actin-binding adapter protein and as a common effector of antigen receptor-signaling pathways in leukocytes. As a key component of the immunological synapse, HIP-55 regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. HIP-55 is degraded by caspases during apoptosis.

宮頸黏液蛋白相關(guān)蛋白抗體保存條件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

性狀：Lyophilized or Liquid

濃度：1mg/1ml

亞型:IgG

純化方法: affinity purified by Protein A

儲(chǔ) 存液: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol

免疫應(yīng)答過(guò)程：

1.抗原進(jìn)入機(jī)體；

2.抗原刺激 B淋巴細(xì)胞，使之分化增殖成為抗體分泌漿細(xì)胞和記憶細(xì)胞（初次免疫應(yīng)答）；

3.抗體主要由漿細(xì)胞分泌；

4.記憶細(xì)胞再次受到特異性抗原刺激后會(huì)被激活而成為分泌抗體的漿細(xì)胞（再次免疫應(yīng)答）；

5.記憶B細(xì)胞是長(zhǎng)命細(xì)胞，可以存活數(shù)月甚至機(jī)體終生。

初次體液免疫是指宿主*次接觸外來(lái)TD抗原后血清中逐漸出現(xiàn)抗原特異性抗體的過(guò)程。初次體液免疫應(yīng)答的延遲相（從抗原免疫到抗體水平達(dá)到高峰的時(shí)間）為6-10天，起初幾天血清中的抗原特異性抗體主要為親和力較低的IgM,后期以IgG為主。初次應(yīng)答過(guò)程的血清中抗原特異性抗體的高峰濃度較低且維持時(shí)間較短。再次體液免疫應(yīng)答是指曾被某抗原免疫過(guò)的宿主再次接觸該抗原時(shí)血清中迅速出現(xiàn)抗原特異性抗體的過(guò)程，其延遲相僅為4-5天，血清抗體以IgG為主，其高峰濃度較高且維持時(shí)間較長(zhǎng)。再次應(yīng)答所產(chǎn)生的抗體還有親和力成熟現(xiàn)象，即該抗體與抗原的親和力明顯高于初次應(yīng)答產(chǎn)生的抗體。

宮頸黏液蛋白相關(guān)蛋白抗體,Anti-HIP55抗體相關(guān)產(chǎn)品：

HEV  戊型肝炎病毒抗體
HGF(hepatocyte growth factor)  肝細(xì)胞生長(zhǎng)因子抗體
HGV（Hepatitis G vivus）  庚型肝炎病毒抗體
ZEBRA/HHV4/EBV（Human herpesvirus 4 type 2/epstein-barr virus ）  類(lèi)皰疹病毒4抗體
HHV8/ORF K2(Human herpesvirus 8)  類(lèi)皰疹病毒8抗體
HHV8/ORF K2(Human herpesvirus 8)  類(lèi)皰疹病毒8抗體
HHV8/ORF50(Human herpesvirus 8 type P)  類(lèi)皰疹病毒8抗體
HHV8/ORF50(Human herpesvirus 8 type P)  類(lèi)皰疹病毒8抗體
HHV8/ORF K2(Human herpesvirus 8 type P)  類(lèi)皰疹病毒8抗體
HIF-1α （YMpoxia-inducible factor -1α）  缺氧誘導(dǎo)因子1α 抗體
HIF-1β/ARNT1(YMpoxia-inducible factor -1β)  缺氧誘導(dǎo)因子1β 抗體
HIF-2α （YMpoxia-inducible factor-2α）  缺氧誘導(dǎo)因子2α 抗體
HINT1（histidine triad nucleotide binding protein 1）  *三聚體核苷結(jié)合蛋白1抗體
Histone H3,Family 3A (HISTIH3I protein)  抗組蛋白3抗體
Histone H1  抗組蛋白H1抗體
Histone H1b/Histone H1.4(Ac-Lys53)  抗乙?；M蛋白H1b抗體
Histone H2/HTB901  抗組蛋白H2抗體
Histone H3-like protein  組蛋白H3樣抗體(Brassica juncea)
Histone H3-like protein  組蛋白H3樣抗體（Brassica junceaC端抗體）
Histone H3-like protein  組蛋白H3樣蛋白抗體（Brassica juncea N端抗體）