Keratocan抗體,品牌細(xì)胞角膜蛋白多糖抗體抗體應(yīng)用于WB、IHC、IF、ELISA等實(shí)驗(yàn)中,產(chǎn)品貨期快、質(zhì)量品牌保障,并提供完善的售前、售中、售后服務(wù)!咨詢或在線客服!我們將竭誠為您服務(wù)!公司堅(jiān)持對(duì)產(chǎn)品質(zhì)量作不斷的評(píng)估、創(chuàng)新和改善以確保您對(duì)我們產(chǎn)品的高度信任!
訂購:或(成)客服
Keratocan抗體,品牌細(xì)胞角膜蛋白多糖抗體產(chǎn)品介紹 Small leucine-rich proteoglycans (SLRPs) such as Decorin, Biglycan, Fibromod-ulin, Keratocan, Lumican and Osteoglycin mediate extracellular matrix organization and are binding partners of TGF Beta. The Decorin core protein binds to growth factors, intercellular matrix molecules such as Fibronectin and Throm-bospondin, and to the Decorin endocytosis receptor. Fibromodulin is a collagen-binding keratan sulphate proteoglycan that influences adhesion processes of connective tissue and plays a role in fibrillogenesis by regulating collagen fibril spacing and thickness. Keratocan (KTN) develops corneal transparency and maintains the stromal matrix structure. Keratocan is a secreted protein in the extracellular matrix that binds to keratan sulfate chains. Keratocan is mainly detected in the cornea, but can also be expressed in trachea, intestine, ovary, lung and skeletal muscle. Defects in the gene encoding for Keratocan can cause cornea plana 2 (CNA2), an autosomal recessive disorder where the forward convex curvature of the cornea is flattened.
細(xì)胞角膜蛋白多糖抗體儲(chǔ)存溫度:存在于血清、組織培養(yǎng)上清液或腹水中的抗體在-20℃下能夠*儲(chǔ)存。低溫存放不會(huì)損傷抗體活性??贵w的工作液通常儲(chǔ)存于4℃中。此溫度下,抗體的活性能穩(wěn)定數(shù)月至數(shù)年亦不損失??贵w溶液不應(yīng)反復(fù)凍融,因?yàn)榉磸?fù)凍融將導(dǎo)致部分抗體失活并產(chǎn)生不需要的蛋白—蛋白凝聚物。抗體的凝聚能導(dǎo)致活性喪失。這是由于抗原結(jié)合位點(diǎn)的空間構(gòu)象被破壞,或由于產(chǎn)生的不溶物被離心或過濾而除去。冷凝蛋白類的抗體不能存放于4℃。因?yàn)樵?℃下此類抗體會(huì)發(fā)生沉淀。一些鼠源性IgG3亞類的抗體有此特性。如果抗體在4℃下發(fā)生沉淀,就應(yīng)該存放于室溫下的疊氮鈉溶液中。
保存條件:低溫
運(yùn)輸:4度,或干冰。
公司抗體具有高純度、高效價(jià)、高特異性的特點(diǎn),僅用于科學(xué)研究,不可用于臨床診斷及藥物治療,可以應(yīng)用于多種實(shí)驗(yàn)。
英文名稱 Keratocan
抗體名稱
別 名 CNA2; KERA; KERA_HUMAN; Keratan sulfate proteoglycan keratocan; Keratocan; KTN; SLRR2B.
研究領(lǐng)域 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞粘附分子 細(xì)胞外基質(zhì)
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
細(xì)胞定位 細(xì)胞外基質(zhì) 分泌型蛋白
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Keratocan
亞 型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
公司更多相關(guān)產(chǎn)品:
YMK-1347R 磷酸化成視網(wǎng)膜細(xì)胞瘤抑癌蛋白抗體 Anti-phospho-Rb/p105-Rb(Ser780)
YMK-11347R *受體δ2/GluR-δ2抗體 Anti-GRID2IP
YMK-2504R 活性氧簇ROS抗體 Anti-ROS/c ros
YMK-12504R 共濟(jì)失調(diào)性眼球運(yùn)動(dòng)功能喪失相關(guān)蛋白AOA1抗體 Anti-AOA1/Aprataxin
YMK-1886R 酸性核糖體磷蛋白大亞基P0抗體 Anti-RPLP0
YMK-11886R Meteorin神經(jīng)膠質(zhì)細(xì)胞分化調(diào)節(jié)蛋白抗體 Anti-METRN
YMK-1205R Rho相關(guān)蛋白激酶2抗體 Anti-ROCK2
YMK-11166R 低密度脂蛋白受體相關(guān)蛋白9抗體 Anti-SorLA/LRP9
YMK-1166R Rho相關(guān)蛋白激酶1抗體 Anti-ROCK1
YMK-2163R 環(huán)指蛋白148抗體 Anti-RNF148
YMK-12163R 鈣磷蛋白2抗體 Anti-Calcyphosine 2/CAPS2
YMK-12125R 氨基酸轉(zhuǎn)運(yùn)蛋白2抗體 Anti-SLC38A2/SNAT2
YMK-2125R 環(huán)指蛋白126抗體 Anti-RNF126
YMK-11480R 軸突導(dǎo)向因子SEMA3E抗體 Anti-SEMA3E/Semaphorin 3E
YMK-1480R RhoC抗體 Anti-Rho C
YMK-1180R RhoA抗體 Anti-RhoA
YMK-11180R 三磷酸腺苷結(jié)合盒轉(zhuǎn)運(yùn)蛋白7抗體 Anti-ABCA7
YMK-0492R G蛋白信號(hào)轉(zhuǎn)導(dǎo)調(diào)節(jié)因子2抗體 Anti-RGS2